How is Cerebral Perfusion Pressure (CPP) calculated?

Cerebral Perfusion Pressure (CPP) is a critical parameter used in neurology and critical care to assess the adequacy of blood flow to the brain. It is calculated as the difference between Mean Arterial Pressure (MAP) and Intracranial Pressure (ICP).

This calculation is grounded in the principle that adequate blood flow to the brain requires a sufficient pressure gradient to overcome any opposing pressures, particularly ICP, which is the pressure within the skull. The formula CPP = MAP - ICP highlights that as ICP increases, the CPP decreases, assuming MAP remains constant. This relationship is crucial in clinical settings because a low CPP can lead to inadequate cerebral blood flow, which may result in ischemia or brain damage.

In summary, the correct calculation of CPP as MAP - ICP is essential for monitoring patients with potential brain injury or increased intracranial pressure to ensure proper cerebral blood supply.