What is the dose of Epinephrine given during ACLS for cardiac arrest?

During Advanced Cardiovascular Life Support (ACLS) for cardiac arrest, the recommended dose of Epinephrine is 1 mg administered every 3-5 minutes. This dosage is based on guidelines established by resuscitation authorities, which aim to enhance the chances of return of spontaneous circulation (ROSC) in patients experiencing cardiac arrest.

Epinephrine works primarily by stimulating alpha and beta adrenergic receptors. The alpha-1 stimulation causes vasoconstriction, which increases systemic vascular resistance and helps improve coronary and cerebral perfusion pressure during cardiopulmonary resuscitation (CPR). The beta-1 stimulation leads to increased heart rate and contractility. By administering 1 mg every 3-5 minutes, you ensure that the myocardium receives continuous sympathetic stimulation, which is crucial during the critical phases of resuscitation.

The guideline to repeat the dose every 3-5 minutes allows for a consistent approach, giving the medication enough time to exert its effects while also repeating it sufficiently to potentially increase perfusion pressures during CPR. This regimen balances the need for effective medication delivery while closely monitoring the patient's response.

The other options propose doses or intervals that do not align with current best practices in resuscitation medicine. For instance, a