What is the maximum dose of Magnesium Sulfate that can be administered for severe asthma in PALS?

In pediatric advanced life support (PALS), magnesium sulfate is commonly utilized as an adjunctive treatment for severe asthma exacerbations. The recommended maximum dose for this use is 2 grams administered intravenously.

Magnesium sulfate acts as a bronchodilator, helping to relax bronchial smooth muscles and improve airflow in patients experiencing severe asthma attacks. Administering up to 2 grams aims to achieve therapeutic effects while minimizing the risk of side effects and toxicity associated with higher doses.

Doses beyond 2 grams may increase the likelihood of adverse reactions, particularly in a pediatric population where the balance between efficacy and safety is crucial. Thus, for severe asthma management in accordance with PALS guidelines, the cap at 2 grams is established to ensure effective treatment while safeguarding the child's health.