What is the normal range for D-Dimer in coagulation laboratory values?

The normal range for D-Dimer levels in coagulation laboratory values can vary slightly depending on the laboratory and its specific reference values. However, a common threshold for a normal D-Dimer result is typically considered to be below 1 mcg/ml. When interpreting this in relation to the options provided, the correct answer aligns with the ranges used in clinical practice for various indications.

D-Dimer is a fibrin degradation product that is used clinically primarily to rule out thromboembolic events such as Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE). Elevated D-Dimer levels can indicate the presence of an abnormal clotting process in the body and are often elevated in conditions such as disseminated intravascular coagulation (DIC), recent surgery, trauma, or malignancy.

The value of 1-5 mcg/ml can be seen in various contexts, particularly in clinical settings where non-specific elevations might still be deemed normal for certain patient populations. While individual laboratories may set slightly different reference ranges based on their assay methodology, the generally accepted upper limit of normal is frequently cited as 1 mcg/ml. Hence, this range acknowledges that while a value of 1 mcg/ml is normal, certain