What is the recommended dose of dopamine infusion in adult ACLS?

Dopamine is a catecholamine used in the management of patients who show signs of hemodynamic instability, particularly in advanced cardiac life support (ACLS) scenarios. The recommended dose of dopamine infusion can vary based on the desired therapeutic effect.

The correct choice reflects the dosage range that primarily focuses on providing increased cardiac output and improving renal perfusion. At doses of 2-10 mcg/kg/min, dopamine acts predominantly on beta-1 adrenergic receptors, leading to increased heart rate and myocardial contractility. This range is often employed in cases where support is needed for cardiac function, as it stimulates the heart to pump more effectively without significantly causing vasoconstriction.

Understanding that specific dose ranges can impact the actions of dopamine is crucial for clinical practice, particularly in emergency situations. Below this range, the drug can have minimal effects, and above 10 mcg/kg/min, the alpha-adrenergic effects can become more pronounced, which could lead to increased systemic vascular resistance and potential complications. Therefore, the choice of 2-10 mcg/kg/min aligns with the goal of optimizing cardiac output and ensuring adequate organ perfusion in an adult patient experiencing shock or cardiac failure within the ACLS framework.