What is the recommended epinephrine infusion dose in adult ACLS?

The recommended epinephrine infusion dose in adult Advanced Cardiac Life Support (ACLS) is 2-10 mcg/kg/min. This dosing range is established to ensure adequate perfusion to vital organs during situations such as cardiac arrest, where epinephrine is used to stimulate the heart and increase coronary and cerebral perfusion pressures.

Using a dose within this range helps to optimize the drug's pharmacologic effects while minimizing the risks of excessive vasoconstriction, which can compromise blood flow to non-essential organs. The aim is to strike a balance that supports effective resuscitation and maintains overall hemodynamic stability.

In clinical practice, careful titration within this dosing range is essential, as patient responses may vary. This allows healthcare providers to adjust infusion rates based on the individual patient's condition and their response to treatment. Understanding this dosing protocol is crucial for anyone involved in advanced cardiac care, ensuring that patients receive the maximum benefit from epinephrine in critical situations.