Which RSI drug is known for having a bronchodilator effect?

Ketamine is recognized for its dual role as both an anesthetic and a bronchodilator. This property makes it particularly beneficial in situations involving patients with reactive airway diseases, such as asthma or chronic obstructive pulmonary disease (COPD). When administered, ketamine can help relax the bronchi, thus improving airflow in the lungs, which is advantageous during rapid sequence intubation (RSI) when airway management is critical.

This bronchodilatory effect is attributed to ketamine's action on the N-methyl-D-aspartate (NMDA) receptor and its influence on the sympathetic nervous system, potentially causing increased bronchial smooth muscle relaxation. Therefore, when considering an RSI drug that can also support respiratory function in certain patients, ketamine stands out for its efficacy in providing both sedation and bronchodilation.